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. 2017 May 18;8(27):44639–44653. doi: 10.18632/oncotarget.17961

Figure 5. Riluzole induces G2/M cell cycle arrest to a greater extent than BAY 36-7620.

Figure 5

MCF-7 (A, B), T-47D (C, D), BT-474 (E, F), MDA-MB-231 (G, H), and BT-549 (I, J) cells were treated with either 25 or 50 μM riluzole or BAY 36-7620 for 24, 48, or 72 h. DNA content was measured by flow cytometry. Data are represented as mean +/− SD. *P < 0.05 compared to DMSO control. **P < 0.005 compared to DMSO control. Representative histograms are shown for 50 μM drug treatment after 72 h for MCF-7 and MDA-MB-231 cell lines (K).