Table 1. Molecular characteristics and drug response of breast cancer cell lines.
Cell line | ER status | GRM1 expression | RiluzoleIC50-μM (SD)* | BAY 36-7620IC50-μM (SD) |
---|---|---|---|---|
MCF-7 | Positive | High | 34.7 (9.9) | 27.7 (5.8) |
T-47D | Positive | Low | 32.6 (4.1) | 37.1 (7.6) |
BT-474 | Positive | Low | 24.2 (4.9) | 20.8 (6.6) |
MDA-MB-231 | Negative | High | 62.4 (10.9) | 41.0 (3.2) |
Hs578T | Negative | Low | 19.0 (2.7) | 21.0 (2.8) |
BT-549 | Negative | High | 24.7 (10.6) | 15.7 (1.3) |
*Values in parentheses represent +/− standard deviation