Table 3. Incidences of treatment-related toxicities in the Pre-S CRT and Pre-S RT groups.
| Acute Toxicities | Pre-S CRT (n = 104) | Pre-S RT (n = 118) | P | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Grade I/II | Grade III/IV | Grade I/II | Grade III/IV | ||||||
| n | % | n | % | n | % | n | % | ||
| Anemia | 46 | 44.2 | 1 | 0.96 | 19 | 16.1 | 0 | 0 | <0.001 |
| Leucopenia | 74 | 71.2 | 11 | 10.6 | 40 | 33.9 | 0 | 0 | <0.001 |
| Thrombocytopenia | 19 | 18.3 | 5 | 4.8 | 3 | 2.55 | 1 | 0.85 | <0.001 |
| Liver function | 3 | 2.9 | 0 | 0 | 6 | 5.1 | 0 | 0 | 0.41 |
| Renal function | 5 | 4.81 | 1 | 0.96 | 2 | 1.7 | 0 | 0 | 0.23 |
| Mucositis | 74 | 71.2 | 29 | 27.9 | 99 | 83.9 | 25 | 21.2 | 0.37 |
| Pharyngalgia | 82 | 78.8 | 14 | 13.5 | 99 | 83.9 | 13 | 11.0 | 0.87 |
| Xerostomia | 103 | 99.0 | 1 | 0.96 | 102 | 86.5 | 0 | 0 | 0.88 |
| Skin reaction | 94 | 90.4 | 6 | 5.8 | 114 | 96.6 | 4 | 3.39 | 0.15 |
Pre-S RT: preoperative radiotherapy; Pre-S CRT: preoperative concurrent chemoradiotherapy.