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. 2017 Aug 7;12(8):e0182471. doi: 10.1371/journal.pone.0182471

Fig 4. Hepatolobectomy induced the selective loss of NMDA receptors in the hippocampus of LPS pretreated mice, but not in age-matched normal adult mice.

Fig 4

Hippocampal synaptic changes analyzed by western blotting. (A-C) Hepatolobectomy reduced the levels of NR2A, NR2B, NR1 in the hippocampus of LPS pretreated mice on day 3. LPS pretreated mice vs. LPS pretreated mice + surgery, p = 0.004 for NR2A, p = 0.03 for NR2B, p = 0.02 for NR1 (D) No significant difference in SYP expression was observed across the groups, p>0.05. LPS pretreated mice (1d) correspond to 6 days survivors, LPS pretreated mice (3d) correspond to 8 days survivors. All data were presented as mean±SEM and analyzed by two-way ANOVA; n = 4 in control part, n = 3 in surgery part; *p<0.05, **p<0.01.