Table 3.

Correlations between CD155 expression and clinicopathological characteristics in CCA

Parameters	Total	CD155 expression		P-value
		Low	High
Age (years)				0.864
≤60	37	14	23
>60	53	21	32
Gender				0.377
Male	54	19	35
Female	36	16	20
Tumor size, mm				0.878
≤30	60	23	37
>30	30	12	18
Tumor location				0.108
Intrahepatic	26	10	16
Perihilar	33	17	16
Distal	31	8	23
PNI				0.361
Absent	46	20	26
Present	44	15	29
LNM				<0.001
Absent	55	30	25
Present	35	5	30
Histological grade				0.002
Moderate–poor	36	7	29
Well	54	28	26
TNM stage				0.03
I–II	57	27	30
III–IV	33	8	25
Serum CA19–9, U/mL				0.561
≤37	13	6	7
>37	77	29	48
Serum CEA, U/mL				0.147
≤5	69	24	45
>5	21	11	10

Abbreviations: CA19–9, carbohydrate antigen19–9; CCA, cholangiocarcinoma; CEA, carcinoembryonic antigen; LNM, lymph node metastasis; PNI, perineural invasion; TNM, tumor-node-metastasis.