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. 2017 Aug 2;10:3881–3891. doi: 10.2147/OTT.S138833

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© 2017 Hu et al. This work is published and licensed by Dove Medical Press Limited

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SHP2 overexpression enhances the proliferation of A2780 cells.

Notes: (A) SHP2-positive foci in 3 wells from each cell line. (B) Anchorage-independent growth was assayed by evaluating colony growth in soft agar. Representative images are shown. The colonies formed by the SHP2-expressing cells are larger in size. Representative images of randomly selected cells from the experimental groups are shown. (C and D) The number of clones in each experimental group was counted. Each experiment was repeated a minimum of 3 times. The data shown here are representative of at least 3 independent experiments with similar results. Significant differences are indicated by asterisks (*P<0.05 and **P<0.01).