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. 2017 Aug 2;10:3867–3880. doi: 10.2147/OTT.S133699

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© 2017 Harrington et al. This work is published and licensed by Dove Medical Press Limited

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Proposed mechanism of action of talimogene laherparepvec. Copyright of Amgen Inc., reproduced with permission.

Abbreviations: GM-CSF, granulocyte–macrophage colony-stimulating factor; HSV-1, herpes simplex virus-1; MHC, major histocompatibility complex; TCR, T cell receptor; TDAs, tumor-derived antigens; T-VEC, talimogene laherparepvec.