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. 2017 Aug 1;10:3861–3866. doi: 10.2147/OTT.S141179

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© 2017 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Analysis of IGF2BP3 expression in HGIN by IHC.

Notes: All images were captured at 200× magnification. Positive (A) and negative (B) staining of IGF2BP3 in pT1a-EP (M1). Positive (C) and negative (D) staining of IGF2BP3 in pT1a-LPM (M2). Positive (E) and negative (F) staining of IGF2BP3 in pT1a-MM (M3). Positive staining of IGF2BP3 was characterized by a dark brown staining in the cytoplasm of the neoplastic cells.

Abbreviations: HGIN, high-grade intraepithelial neoplasia; IGF2BP3, insulin-like growth factor-II mRNA-binding protein-3; IHC, immunohistochemistry.