Figure 1.

Trial design.

Notes: ^aThe time of the active olanzapine dose (morning or afternoon/evening) was not disclosed in order to preserve blinding. If the active olanzapine dose was taken in the morning, the olanzapine-matched placebo was taken in the afternoon/evening; if the active olanzapine dose was taken in the afternoon/evening, the olanzapine-matched placebo was taken in the morning. The same number of film-coated tablets was taken in the morning and afternoon/evening.

Abbreviations: BID, twice daily; EOT, end of treatment; QD, once daily.