Skip to main content
. 2017 May 12;102(8):2862–2872. doi: 10.1210/jc.2017-00612

Figure 3.

Figure 3.

Dominant-negative effect of PCOS-specific AMH variants on signaling. Average BRE-firefly luciferase induction normalized to Renilla reporter and empty vector control in COS7 cells transfected with REF and/or variant AMH constructs. PCOS-specific AMH variants are shown in orange, and AMH variant present only in control subjects is shown in green. Solid colors indicate homozygous state, and the diagonal line pattern indicates the heterozygous state. Results represent three independent experiments done in triplicate with standard error of the mean. REF, reference.