Table 1.

Risk for Developing Multiple Autoantibodies Within 5 Years in Single Autoantibody–Positive Relatives Categorized by Age

Antibody Type	Age at Entry, y				Overall
	<8	8–11	12–17	>18
GADA, n	107	113	117	372	709
Risk, %	35 (24–46)	38 (24–51)	28 (14–41)	16 (10–22)	25 (20–30)
IAA, n	69	33	43	91	236
Risk, %	37 (22–52)	4 (0–11)	13 (0–34)	13 (0–25)	19 (11–27)
IA-2A, n	7	11	9	22	49
Risk, %	Insufficient number of participants to assess				23 (7–38)

Values in parentheses are 95% CIs.