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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Nanomedicine. 2017 Apr 19;13(6):1983–1992. doi: 10.1016/j.nano.2017.04.005

Figure 6. Expression of profibrotic genes in lung tissues of mice with pulmonary fibrosis.

Figure 6

Pulmonary fibrosis was induced by intratracheal instillation of 1.5 U/kg of bleomycin. Mice were treated with substances indicated twice a week for three weeks starting one day later after the bleomycin administration. At the end of treatment, lungs were harvested and homogenized The expression of genes encoding transforming growth factor-β cytokines (TGFB1-3), transforming growth factor-β receptors (TGFBR1-2) and smooth muscle α actin (CTGF) was measured by the QPCR and presented as fold change relative to the healthy animals. Means ± SD are shown. *P < 0.05 when compared with control mice.