Figure 2.

Modeled structure of CLE42-PXL2 ^LRR and PXL2^LRR-CLE42-SERK2^LRR. (A) Crystal structure of PXL2^LRR alone shown in cartoon. (B) Modeled structure of PXL2^LRR-CLE42 complex using as the PXY^LRR-CLE41 template. CLE42 adopts an “Ω”-like kink and binds to the concave surface of PXL2^LRR. (C) Detailed interaction of the N-terminal side of CLE42 with PXL2^LRR. The side chains of some amino acids from CLE42 and PXL2^LRR are shown in violet and yellow orange, respectively. Yellow dashed lines indicate hydrogen bonds or salt bridges. (D) Detailed interaction of the central region of CLE42 with PXL2^LRR. (E) Detailed interaction of the C-terminal side of CLE42 with PXL2^LRR. (F) Model structure of PXL2^LRR-CLE42-SERK2^LRR complex. (G) Detailed interaction between the C-terminal residues Ser11 and Asn12 of CLE42 and PXL2, SERK2. The side chains of some amino acids from CLE42, PXL2^LRR, and SERK2^LRR are shown in violet, yellow orange, and pink, respectively. Yellow dashed lines indicate hydrogen bonds or salt bridges. (H) Detailed interaction between PXL2^LRR-CLE42 and SERK2^LRR