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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Am J Hematol. 2017 Jul 19;92(9):E520–E528. doi: 10.1002/ajh.24810

Figure 1. Percent of participants meeting the primary endpoint by baseline class of albuminuria.

Figure 1

The primary endpoint of a ≥25% reduction in urinary albumin-to-creatinine ratio (UACR) from baseline was met in 67% (12/18) of participants with albuminuria and 41% (13/32) of all participants. Most participants in the MicroA and MacroA groups met the primary endpoint. The dotted line indicates 30% of participants having a ≥25%reduction in UACR, which was the minimum anticipated proportion of participants with ≥25% reduction in UACR in the MicroA group used for calculation of sample size. P-values are from a two-sided binominal test, assuming that the proportion of significant reduction (≥25%) in UACR without losartan was ≤5%.