Table 1.
Baseline characteristics of all participants and by class of baseline albuminuria.
| Characteristic | All participants (N or mean ± SEM) | No albuminuria (N or mean ± SEM) | Micro-albuminuria (N or mean ± SEM) | Macro-albuminuria (N or mean ± SEM) | P* |
|---|---|---|---|---|---|
| Number | 32 | 14 | 12 | 6 | |
| Sex (male/female) | 14/18 | 8/6 | 4/8 | 2/4 | |
| Age (years) | 24.4 ± 15.7 | 14.6 ± 1.3 | 28.6 ± 4.8 | 38.8 ± 7.0 | <0.01 |
| Hb (g/dL) | 8.7 ± 2.3 | 9.2 ± 3.5 | 8.3 ± 3.6 | 8.4 ± 4.7 | 0.14 |
| UACR (mg/g) | 202 ± 59 | 8.5 ± 1.3 | 121 ± 25 | 815 ± 137 | <0.01 |
| eGFR-CrCl (mL/min/1.73m2) | 150 ± 10 | 146 ± 61 | 172 ± 59 | 108 ± 19 | 0.02 |
| eGFR-CysC (mL/min/1.73m2) | 134 ± 6.4 | 132 ± 5.0 | 155 ± 11.9 | 96 ± 9.6 | <0.01 |
| Osmolality (mosm/kg H20) | 393 ± 12 | 430 ± 21 | 383 ± 10 | 328 ± 21 | <0.01 |
| SBP (mm Hg) | 116 ± 2.1 | 116 ± 3.4 | 114 ± 3.5 | 120 ± 4.3 | 0.60 |
| DBP (mm Hg) | 65 ± 1.2 | 60 ± 1.3 | 68 ± 1.8 | 67 ± 2.7 | <0.01 |
*
Independent samples Kruskal-Wallis test of the distribution of the continuous variables across the three classes of baseline albuminuria.
Abbreviations: DBP, diastolic blood pressure; eGFR-CrCl, estimated glomerular filtration rate by creatinine clearance from 24-hour urine collection; eGFR-CysC, estimated glomerular filtration rate by measurement of cystatin C; Hb, hemoglobin concentration; SBP, systolic blood pressure; SEM, standard error of the mean; UACR, urinary albumin-to-creatinine ratio.