Fig. 9. A unique spatial arrangement of the U snRNPs within the native spliceosome emerges from in-silico studies.
[69]. The native spliceosome is transparent; U4/U6.U5 tri-snRNP is colored by functional regions, with U5 snRNP in pink and the region attributed to loop I in black [83]; U4/U6 in beige-orange; U2 snRNP subcomponent SF3b is in green; and U1 snRNP is blue. Adapted from Ref [69].