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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Feb 21;140(2):454–464.e2. doi: 10.1016/j.jaci.2017.02.001

Figure 3. Upregulation of pro-pruritic and downregulation of anti-pruritic genes in the spinal cord of IL-31Tg mice.

Figure 3

(A–C) In IL-31Tg mice (red), spinal cord mRNA levels of the GABA-B1 receptor (B) decreased; GRP and PPTA mRNA (C) increased. Expression of GAD 65/67 (A), GABA-A receptor subunits (B) or GRP- and NK1-receptors (C) did not change. Data: ± SEM; * P<0.05; ** P<0.005; NS = not significant; Student’s t-test.