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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Feb 21;140(2):454–464.e2. doi: 10.1016/j.jaci.2017.02.001

Figure 4. Transplant-mediated reduction of scratching, skin lesions and spinal cord activity in IL-31Tg mice.

Figure 4

Skin lesions (A–I) and scratching (J; N=10 vs 9 controls) reduced only after MGE-transplant. Data: ± SEM; * relative to baseline; # relative to control; * P<0.05; ** P<0.005; ## P<0.05; NS = not significant; two-way ANOVA and Bonferroni post-hoc. (K–O) MGE transplants reduced scratching-induced dorsal horn Fos+ neurons (N; red bar in O). BL= baseline. Data: ± SEM; * P<0.05; Student’s t-test. Scale bar: 100 μm.