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. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: Biol Psychiatry. 2017 Mar 28;82(5):361–369. doi: 10.1016/j.biopsych.2017.03.011

Table 1.

Comparison of baseline wrist activity levels on Day 1 (D1) following ketamine or placebo

CONTRAST		Individual Parameters			Combined
CONTRAST		Mesor (counts)	Amplitude (counts)	Acrophase (hh:mm)	P	F
Ketamine: Baseline vs D1 (n = 51)	Baseline	158.9 ± 3.7 (a)	118.8 ± 5.24	14:40 ± 0:09	0.0005^***	5.940 (3,2404)
Ketamine: Baseline vs D1 (n = 51)	D1	140.4 ± 3.69 ^†††	107.5 ± 5.23	14:14 ± 0:11	0.0005^***	5.940 (3,2404)
Placebo: Baseline vs D1	Baseline (n = 38)	159.8 ± 3.95	117.6 ± 5.59	14:50 ± 0:11	0.3917	1.000 (3,1690)
Placebo: Baseline vs D1	D1 (n = 34)	153.4 ± 4.84	114.4 ± 6.82	14:26 ± 0:14	0.3917	1.000 (3,1690)
Ketamine vs Placebo: D1	Ketamine Infusion (n =51)	140.4 ± 3.69	107.5 ± 5.23	14:14 ± 0:11	0.123	1.928 (3,1974)
Ketamine vs Placebo: D1	Placebo Infusion (n= 34)	153.4 ± 4.84	114.4 ± 6.82	14:26 ± 0:14	0.123	1.928 (3,1974)

Mean Estimate ± SEM

For overall curve fit difference:

^*

p < .05

^**

p < .01

^***

p < .001

For independent parameter tests:

^†

p < .05

^††

p < .01

^†††

p < .001