Table 2.
Seed region | Region | BA | Cluster size | MNI coordinates | T value | P (FDR) | ||
---|---|---|---|---|---|---|---|---|
X | Y | Z | ||||||
CON > SCZ | ||||||||
Lobule V | Middle frontal gyrus (MFG) | 9 | 171 | −42 | 12 | 48 | 4.68 | 0.008 |
Ventral premotor cortex | 6 | −38 | 2 | 38 | 3.51 | |||
Anterior cingulate cortex | 32 | 428 | 10 | 50 | 22 | 4.44 | <0.001 | |
Superior frontal gyrus (SFG) | 8 | −2 | 36 | 48 | 4.27 | |||
9 | −8 | 42 | 42 | 4.21 | ||||
MFG | 9 | 189 | −22 | 46 | 32 | 4.34 | 0.007 | |
9 | −20 | 40 | 20 | 4.01 | ||||
SFG | 46 | −24 | 52 | 18 | 3.65 | |||
Thalamus | Thalamus | – | 416 | −14 | −14 | 4 | 4.35 | <0.001 |
14 | −12 | 12 | 4.33 | |||||
8 | −4 | 8 | 4.32 | |||||
Lateral M1 | Supplementary motor area (SMA) | 6 | 595 | −6 | −14 | 58 | 4.97 | <0.001 |
Medial motor cortex | 4 | −10 | −28 | 60 | 4.35 | |||
−6 | −28 | 72 | 4.25 | |||||
SCZ > CON | ||||||||
Crus I | Parahippocampal gyrus | 27 | 328 | 16 | −30 | −4 | 4.75 | <0.001 |
30 | 20 | −24 | −10 | 4.02 | ||||
Lingual gyrus | 17 | 14 | −58 | 6 | 3.99 | |||
Thalamus | Somatosensory cortex (S1) | 3 | 854 | 50 | −16 | 30 | 5.60 | <0.001 |
Premotor/primary motor cortex (M1) | 6 | 38 | −12 | 52 | 4.67 | |||
42 | −8 | 38 | 4.48 | |||||
S1 | 3 | 981 | 24 | −40 | 54 | 5.15 | <0.001 | |
Precuneus/S1 | 5 | −6 | −38 | 60 | 4.77 | |||
Medial motor cortex | 4 | −8 | −26 | 58 | 4.54 | |||
Lateral occipital cortex (LOC) | 19 | 1533 | 22 | −78 | 26 | 4.67 | <0.001 | |
19 | −16 | −78 | 40 | 4.61 | ||||
Precuneus | 18 | −12 | −76 | 32 | 4.45 | |||
Middle temporal gyrus (MTG) | 37 | 357 | −50 | −62 | 10 | 4.55 | <0.001 | |
LOC | 37 | −40 | −64 | 8 | 4.51 | |||
−44 | −68 | 2 | 4.36 | |||||
S1 | 3/48 | 174 | −44 | −16 | 30 | 4.44 | 0.006 | |
M1 | 6 | −40 | −8 | 36 | 4.15 | |||
S1 | 3 | −34 | −18 | 34 | 3.92 | |||
MTG | 37 | 143 | 40 | −58 | 2 | 4.27 | 0.014 | |
37 | 48 | −52 | 2 | 3.84 | ||||
48 | −66 | 4 | 3.43 | |||||
Lateral M1 | Thalamus | – | 856 | 10 | −8 | 10 | 5.85 | <0.001 |
– | −8 | −18 | 10 | 4.88 | ||||
−6 | −10 | 6 | 4.55 |
Results of the contrasts looking at the SCZ and CON groups relative to one another are presented above. Bolded rows indicate peak voxels within the given cluster.