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. 2017 Aug 7;7:7471. doi: 10.1038/s41598-017-08264-8

Figure 3.

Figure 3

GO and KEGG analysis of differentially modulated genes in alveolar macrophages in Abt mice. The mice in Abt group were given antibiotics for five weeks. Purified alveolar macrophages (F4/80hi CD11chi) were analyzed by GeneChip. (a) An overview of the biological pathway analysis. BiNGO was used to categorize GO biological processes and generate a pathway enrichment network. (b) The list of DEGs was converted into Entrez-IDs for GO analysis with R 3.2.3 using the library GOstats 2.34.0 and the R Bioconductor genomewide mouse annotations from the package org.Mm.eg.db (version 3.3.0). (c) The list of DEGs was converted into Entrez-IDs for KEGG analysis with R 3.2.3 using the library GOstats 2.34.0 and the R Bioconductor genomewide mouse annotations from the package org.Mm.eg.db (version 3.3.0).