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. 2017 Aug 7;7:7386. doi: 10.1038/s41598-017-07782-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Estimates of site-specific drug efficacies calculated from model fits to intervention community trial data. The 500 parameter vectors fitted to baseline conditions were used to project the impact of DEC-medicated salt with each vector simulated 500 times via sampling from an initial range of plausible drug parameter values. Intervention survey data used to accept or reject a parameter vector are represented by red crosses with 95% binomial error bars in the main plot axes. Gray curves are the model fits which ultimately informed the monthly worm and mf kill rates. Inset plots show the posterior relative frequency distributions of the monthly worm and mf kill rates for each site.