Table 1.
Comparison of variables among subsites of oral squamous cell carcinoma patients.
| Lip (n = 54) | Gum (n = 218) | FOM (n = 33) | Tongue (n = 417) | Buccal (n = 556) | Palate (n = 74) | RMT (n = 27) | P | |
|---|---|---|---|---|---|---|---|---|
| Age [Mean (SD)] | 52.4(9.8) | 55.9(11.6) | 51.7(7.0) | 51.3(11.3) | 52.7(10.9) | 55.2(11.8) | 52.3(9.4) | <0.001 |
| Gender [Male (%)] | 53(98.1) | 203(93.1) | 37(100) | 364(87.3) | 541(97.3) | 72(97.3) | 27(100) | <0.001 |
| Smoking (%) | 48(88.9) | 182(83.5) | 35(94.6) | 319(76.9) | 504(90.6) | 60(81.1) | 26(96.3) | <0.001 |
| Betel quid (%) | 48(88.9) | 177(81.2) | 35(94.6) | 289(69.3) | 503(90.5) | 58(78.4) | 23(85.2) | <0.001 |
| Alcohol (%) | 39(72.2) | 165(76.7) | 36(97.3) | 278(66.7) | 413(74.3) | 50(67.6) | 20(74.1) | 0.002 |
| Histological grade | 0.004 | |||||||
| WD (%) | 10(18.5) | 16(7.3) | 2(5.4) | 22(5.3) | 62(11.2) | 9(12.2) | 1(3.7) | |
| MD (%) | 35(64.8) | 161(73.9) | 26(70.3) | 280(67.1) | 360(64.7) | 47(63.5) | 23(85.2) | |
| PD (%) | 9(16.7) | 41(18.8) | 9(24.3) | 115(27.6) | 134(24.1) | 18(24.3) | 3(11.1) | |
| Perineural invasion (%) | 11(20.4) | 33(15.1) | 9(24.3) | 131(31.4) | 119(21.4) | 5(6.8) | 6(22.2) | <0.001 |
| Lymphvascular invasion (%) | 7(13.0) | 50(22.9) | 12(32.4) | 138(33.1) | 132(23.1) | 12(16.2) | 9(33.3) | 0.001 |
| Extracapsular spread | 8(14.8) | 36(16.5) | 11(29.7) | 82(19.7) | 79(14.2) | 10(13.5) | 4(14.8) | 0.108 |
| Surgical margin <5mm (%) | 8(14.8) | 43(19.7) | 9(24.3) | 45(10.8) | 108(19.4) | 18(24.3) | 4(14.8) | 0.004 |
| Pathological stage | <0.001 | |||||||
| Stage I and II (%) | 35(64.8) | 55(25.2) | 14(37.8) | 188(45.1) | 235(32.3) | 42(56.8) | 13(48.1) | |
| Stage III and IV (%) | 19(35.2) | 163(74.8) | 23(62.2) | 229(54.9) | 321(57.7) | 32(43.2) | 14(51.9) | |
| Postoperative radiation (%) | 19(35.2) | 95(43.6) | 22(59.5) | 210(50.4) | 261(46.9) | 33(44.6) | 14(51.9) | 0.196 |
| Loco-regional recurrence (%) | 16(29.6) | 81(37.2) | 16(43.2) | 151(36.2) | 187(33.6) | 26(35.1) | 12(44.4) | 0.687 |
| Distant metastasis (%) | 3(5.6) | 14(6.4) | 5(13.5) | 45(10.8) | 59(10.6) | 3(4.1) | 4(14.8) | 0.174 |
| Cancer death (%) | 11(20.4) | 41(18.8) | 10(27.0) | 109(26.1) | 151(27.2) | 20(27.0) | 7(25.9) | 0.329 |
| 5-year DSS (all stage, %) | 85.76 | 81.39 | 68.89 | 74.56 | 77.58 | 75.18 | 85.25 | 0.4530 |
| Stage I and II (%) | 88.91 | 87.19 | 90.91 | 86.23 | 86.41 | 77.78 | 100 | 0.8745 |
| Stage III and IV (%) | 54.14 | 72.66 | 43.10 | 53.70 | 55.78 | 64.28 | 51.43 | 0.0256 |
SD: standard deviation; WD: well differentiated; MD: moderately differentiated; PD: poorly differentiated; FOM: floor of mouth; RMT: retromolar trigone; DSS: disease-specific survival.