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. 2017 Aug 7;7:7388. doi: 10.1038/s41598-017-06854-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Entropy growth per subject. (a) Boxplot of the entropy distribution and before (B) and after (A) Ayahuasca ingestion and (b) boxplot of entropy increase, for all 7 subjects. Note the significant increase in entropy after Ayahuasca ingestion. There are 16 values of entropy per subject, as discussed in the text. The bars show minimum and maximum values and the box shows the 2nd and 3th quartiles, with the median shown dividing the box (in red). The asterisks (*) in the bottom rows in both plots indicate p-values p < 0.005 for Student’s paired t-test in (a) and t-test for zero mean in (b). Subject-by-subject, we thus find strong evidence against the null hypothesis of no entropy change.