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FKA induces G2M arrest in HER2-overexpressing MCF7/HER2 and SKBR3 cells and G1 arrest in HER2 less MCF7 cells. MCF7, MCF7/HER2, and SKBR3 cells were treated with 0.05% DMSO or 16 μM FKA for 24 h. Cell cycle population was determined by FACS analysis. (A) Quantitative analysis of the percentage of cell cycle phase; and (B) graphical presentation of cell cycle distribution after FKA treatment.
