Fig. 2.

Allocation and effects of therapies. For primary (left), escalating (center) and second escalating (right) relapse treatment, the solid bar indicates the number of patients with indication for relapse treatment, the grey-shaded bar indicates applied treatment type, and the hatched bar indicates the effect of treatment, assessed clinically 10–14 days after treatment conclusion; the percentages of treatment response is given to the right of the hatched bar. IA, immunoadsorption; MP, methylprednisolone i.v.; PLEX, plasma exchange