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. 2017 Aug 7;7:38. doi: 10.1186/s13578-017-0166-2

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Roles of miR-290-295 cluster in enhancing somatic reprogramming. miR-290-295 cluster can enhance the reprogramming efficiency by promoting MET and cell-cycle progression in the early stage of reprogramming. In addition, it also enhances the expression of core transcription factors, such as Oct4, Sox, c-Myc, Nanog et al. in late stage