Table 1.

Patients’ data overview

	Humerus		Femur		Tibia
	with rhBMP-7	without rhBMP-7	with rhBMP-7	without rhBMP-7	with rhBMP-7	without rhBMP-7
Group size	13	9	28	13	21	28
Gender: Male / female	7 / 6	6 / 3	17 / 11	11 / 2	14 / 7	20 / 8
Age [years]	49.0 ± 4,7	51.0 ± 4.2	55.2 ± 2.6	42.4 ± 3.8	51.6 ± 2.7	42.3 ± 2.6
Closed / open fracture	11 / 2	7 / 2	24 / 4	10 / 3	14 / 7	18 / 10
Nicotine abuse	6	2	4	1	10	6
Diabetes mellitus	2	0	2	1	4	0
Steroid therapy	0	0	1	0	0	0
Charlson comorbidity index [33]	0.23 ± 0.12	0.33 ± 0.17	0.41 ± 0.15	0.31 ± 0.17	0.38 ± 0.16	0.14 ± 0.08
Period of time between index operation and revision surgery [months]	14.8 ± 3.8		11.7 ± 1.1		10.3 ± 2.6

Results are presented as mean ± standard error of the mean (SEM) or median