. Author manuscript; available in PMC: 2018 May 1.

Published in final edited form as: JAMA Neurol. 2017 May 1;74(5):540–548. doi: 10.1001/jamaneurol.2016.5953

Table 2.

Summary of Clinical Visits and Neuropsychological (NP) Tests by Braak Stages

	Braak stage
	Low (0/1/2)	Moderate (3/4)	High (5/6)
Average number of clinical visits per subject within 3 years before death (#visits / #subjects)
CDR-SOB^a	1.94 (95/49)	1.96 (313/160)	1.93 (1292/668)
Logical memory^a	1.88 (75/40)	1.92 (236/123)	1.72 (592/344)
Vegetable naming^a	1.80 (79/44)	1.93 (235/122)	1.71 (623/365)
Time from last clinical visit to death, Median (IQR), year
	0.56 (0.45, 0.93)	0.75 (0.43, 1.25)	0.89 (0.47, 1.73)
Neuropsychological (NP) tests results at the last clinical visit, Median (IQR)
CDR-SOB	0 (0, 6.0)	5.75 (1.0, 12.0)	16.0 (10.0,18.0)
Logical memory	12 (9.0, 14.0)	6.0 (2.0, 10.0)	1.0 (0, 4.0)
Vegetable naming	10.0 (6.0, 12.0)	6.0 (3.0, 10.0)	3.0 (1.0, 6.0)

Abbreviations: IQR, interquartile range.

CDR-SOB was measured at each clinical visit for all the participants who had clinical visits within 3 years before death. The other two neuropsychological tests, logical memory and vegetable naming, were not available for certain participants.