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. 2017 Jul 17;114(31):8241–8246. doi: 10.1073/pnas.1620220114

Table S4.

Time dependence of the growth-inhibitory activity of NSAH and gemcitabine

Cell line Drug exposure, h Drug IC50, µM
MDA-231 2 NSAH >10.0
MDA-231 6 NSAH >10.0
MDA-231 24 NSAH 0.658
MDA-231 72 NSAH 0.498
MDA-231 2 GEM 1.930
MDA-231 6 GEM 1.540
MDA-231 24 GEM 0.274
MDA-231 72 GEM 0.100
HCT116 2 NSAH >10.0
HCT116 6 NSAH >10.0
HCT116 24 NSAH 0.572
HCT116 72 NSAH 0.221
HCT116 2 GEM 0.487
HCT116 6 GEM 0.343
HCT116 24 GEM 0.058
HCT116 72 GEM 0.030
Panc1 2 NSAH >10.0
Panc1 6 NSAH >10.0
Panc1 24 NSAH 0.898
Panc1 72 NSAH 0.442
Panc1 2 GEM 0.680
Panc1 6 GEM 0.406
Panc1 24 GEM 0.084
Panc1 72 GEM 0.046