Fig. 1.

Probe development for separating overlapping pathologies. (A) Pathologies such as infection, inflammation, and cancer often have overlapping conventional imaging features. Distinction between such basic underlying pathologies with probe development can be important for accurate diagnosis or monitoring of therapy, such as in the case of bacterial infection. (B) Synthetic scheme for ¹⁸F-radiolabeled trimethoprim, [¹⁸F]FPTMP, for imaging bacterial infection.