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. 2005 Feb 24;4:14. doi: 10.1186/1475-2875-4-14

Table 2.

Treatment endpoints on day 28, 42 after treatment and PCR adjusted day 42, Malakal, Upper Nile, Sudan, 2003–2004

AS + AQ AS + SP
N % 95% CI N % 95% CI
Day 28 Results 117 116
 ACPR 105 89.7 82.8–94.6 114 98.3 93.9 – 99.8
 ETF 0 0 1 0.9 0.0–4.7
 LCF 10 8.5 4.2–15.2 1 0.9 0.0–4.7
LPF 2 1.7 0.2–6.0 0 0

Day 42 Results 113 116
 ACPR 96 85.0 77.0–91.0 112 96.6 91.4–99.1
 ETF 0 0 1 0.9 0.0–4.7
 LCF 15 13.3 7.6–20.9 2 1.7 0.2–6.1
 LPF 2 1.8 0.2–6.2 1 0.9 0.0–4.7

PCR corrected day 42# 97 113
  No PCR result (12) (2)
  Re-infections (4) (1)
 ACPR 96 99.0 94.4–100 112 99.1 95.2–100
 ETF 0 0 0.0–3.7 1 0.9 0.0–4.8
 LCF 1 1.0 0.0–5.6 0 0 0.0–3.2
 LPF 0 0 0.0–3.7 0 0 0.0–3.2

#Cases with missing or undetermined PCR results and re-infections were excluded from the analysis. ACPR = Adequate Clinical Parasitological Response, ETF = Early Treatment Failure, LCF = Late Clinical Failure, LPF = Late Parasitological Failure.