Table 3.

Measurement of YM in the renal cortex, medulla and sinus of beagle’s kidneys with varying renal perfusion ex vivo

Ligation status	Cortex (Kpa, n = 6)			Medulla (Kpa, n = 6)			Sinus (Kpa, n = 6)
	0 mmHg	75 mmHg	150 mmHg	0 mmHg	75 mmHg	150 mmHg	0 mmHg	75 mmHg	150 mmHg
No ligation	12.23 ± 0.83	52.99 ± 6.77**	87.50 ± 2.36**	12.26 ± 1.88	35.56 ± 2.48**	66.95 ± 2.34**	18.32 ± 1.91	44.86 ± 3.86**	89.23 ± 7.39**
Vein ligation	12.15 ± 1.06	52.79 ± 11.37**	81.63 ± 13.33**	12.81 ± 1.91	36.85 ± 2.48**	52.39 ± 7.20**	20.65 ± 3.91	46.48 ± 5.19**	86.81 ± 10.48**
Combined ligation	12.79 ± 2.48	47.31 ± 13.40**	101.39 ± 5.61**##	16.70 ± 5.36	37.59 ± 4.72**	79.42 ± 3.68**##	23.06 ± 3.59	47.12 ± 1.78**	104.60 ± 17.00**

Values are given as the mean ± SD. Measurements were obtained at the mid-portion of the kidneys. Using paired t-test or ANOVA analysis. Compared with 0 mmHg: ^** P<0.01. Compared with no ligation: ^## P<0.01