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. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Clin Microbiol Infect. 2016 Sep 15;23(1):48.e9–48.e16. doi: 10.1016/j.cmi.2016.09.003

Table 2. Economic burden (($US, median (95% credibility range)) and QALYs lost because of CRE infection by type of infection assuming meropenem use for carbapenem therapies.

Bacteraemia Intra-abdominal infection Non-VAP VAP UTI
Attributable mortality 26%
Hospital perspective 35 532 (32 516–39 280) 65 815 (51 794–81 005) 26 336 (14 646–38 473) 45 359 (36 682–54 235) 22 678 (14 680–31 068)
Third-party payer perspective 16 509 (14 378–18 948) 18 924 (16 585–22 472) 23 724 (19 625–28 520) 31 622 (26 577–36844) 10 543 (8967–12 564)
Productivity losses because of absenteeism 1354 (619–5526) 2454 (1059–10 172) 930 (342–4374) 1688 (754–6929) 853 (302–3606)
Productivity losses because of death 48 106 (17 523–168 916) 33 337 (12 144–117 060) 42 507 (15 484–149 258) 2599 (947–9126) 36 875 (13 432–129 482)
Societal perspective 66 363 (35 558–185 503) 55 634 (33 184–139 461) 67 427 (40 422–175 054) 36 706 (30 357–45 637) 48 519 (24 823–140 346)
QALYs lost 1 (1–2) 1 (1–1) 1 (1–1) 0 (0–0) 1 (1–1)
Attributable mortality 35%
Hospital perspective 35 980 (32 525–39 089) 65 663 (51 802–80 719) 26 190 (14 672–38 622) 45 694 (36 630–54 382) 22 569 (14 640–30 822)
Third-party payer perspective 16 365 (14 455–19 023) 18 844 (16 573–22 515) 23 669 (19 567–28 294) 31 565 (26 503–37 222) 10 485 (8959–12 617)
Productivity losses because of absenteeism 1363 (630–5136) 2520 (1059–9702) 973 (321–4396) 1760 (739–6671) 843 (308–3120)
Productivity losses because of death 66 269 (25 421–237 397) 45 925 (17 617–164 518) 58 557 (22 462–209 769) 3580 (1373–12 826) 50 798 (19 486–181 976)
Societal perspective 84 795 (43 018–256 352) 68 643 (38 972–187 163) 83 545 (46 510–232 828) 38 105 (31 030–48 168) 62 720 (30 714–194 194)
QALYs lost 1 (1–2) 1 (1–1) 1 (1–2) 0 (0–0) 1 (1–2)
Attributable mortality 44%
Hospital perspective 35 321 (32 558–39 236) 65 896 (51 443–80 403) 26 336 (14 631–38 511) 45 782 (36 677–54 405) 22 622 (14 584–31 150)
Third-party payer perspective 16 594 (14 403–19 009) 19 053 (16 613–22 564) 23 722 (19 617–28 234) 31 813 (26 282–37 351) 10 628 (8937–12 629)
Productivity losses because of absenteeism 1383 (621–4878) 2584 (1058–9402) 1025 (310–4006) 1771 (756–6424) 870 (310–3178)
Productivity losses because of death 78 320 (28 780–309 447) 54 276 (19 945–214 449) 69 205 (25 431–27 3434) 4231 (1555–16 719) 60 036 (22 061–237 205)
Societal perspective 97 288 (47 215–327 373) 77 281 (42 532–23 6905) 95 765 (50 771–297 385) 39 103 (31 328–51 935) 71 944 (33 921–248 597)
QALYs lost 2 (1–3) 1 (1–2) 2 (1–2) 0 (0–0) 1 (1–2)