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. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Clin Microbiol Infect. 2016 Sep 15;23(1):48.e9–48.e16. doi: 10.1016/j.cmi.2016.09.003

Table 3. Epidemiologic and economic burden (median (95% credibility range), costs in millions ($US)) of CRE infections in the United States assuming a 26% attributable mortality and meropenem use for carbapenem therapies.

CRE incidence per 100 000

2.93 6 10 15
Infections 9418 19 285 32 142 48 213
Deaths 840 1721 2868 4301
QALYs lost 8841 (5805–12 420) 18 105 (11 888–25 433) 30 174 (19 814–42 388) 45 261 (29 720–63 581)
Hospital perspective 275 (217–334) 562 (443–685) 937 (739–1141) 1406 (1109–1712)
Third-party payer perspective 147 (129–172) 302 (264–353) 503 (440–588) 754 (661–882)
Productivity losses because of absenteeism 11 (5–46) 22 (9–94) 37 (16–157) 56 (24–236)
Productivity losses because of death 389 (149–1407) 796 (306–2882) 1327 (509–4803) 1990 (764–7205)
Societal perspective 553 (303–1593) 1132 (620–3262) 1886 (1034–5437) 2830 (1550–8155)