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Impact of viral infection on IFN-pathway activation. FRhL2 cells were transfected with p55C1BLuc, a plasmid containing an IRF3-activated IFN-β promoter element that drives luciferase expression. The cells were mock-infected or infected with the indicated virus, and, at 10 h after infection, cellular lysates were assayed for luciferase activity. The values are reported as fold increase in luciferase activity relative to mock-infected cells.
