Skip to main content
. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Nat Genet. 2012 Dec 23;45(2):186–190. doi: 10.1038/ng.2508

Figure 5.

Figure 5

Reduced Not3 expression promotes tumor development in a Drosophila sensitized background. (a,b) Sensitized flies overexpressing the Notch ligand Delta in the eye were crossed to one of three different Drosophila Not3 RNAi fly lines (v105990, v37545, v37547), to the 15271 line with a P-element insertion in Not3 or to control RNAi flies (with an RNAi construct against the white (w) gene). Shown are quantitative (a) and qualitative (b) representations of the eye tumor burden in different genotypes. ***, tumor incidence in this cross was significantly different from that in the control cross (P < 0.001) as analyzed by two-tailed Fisher’s exact test. Scale bars in b, 200 µm.