Table 1. Demographic and Clinical Characteristics for Patients With Pain Response at Day 42 With Quality-of-Life Dataa.
| Characteristic | Responders (n = 102) |
Nonresponders (n = 85) |
P Valueb |
|---|---|---|---|
| Age, median (range), y | 68.5 (34-95) | 68.0 (43-94) | .60 |
| Sex | |||
| Male | 61 (59.8) | 39 (45.9) | .06 |
| Female | 41 (40.2) | 46 (54.1) | |
| Primary cancer | |||
| Prostate | 40 (39.2) | 14 (16.5) | .007 |
| Breast | 25 (24.5) | 26 (30.6) | |
| Lung | 18 (17.6) | 25 (29.4) | |
| Other | 19 (18.6) | 20 (23.5) | |
| Baseline Karnofsky performance status | |||
| 40-60 | 14 (13.7) | 13 (15.3) | .87 |
| 70-80 | 57 (55.9) | 49 (57.6) | |
| 90-100 | 31 (30.4) | 23 (27.1) | |
| Baseline worst pain score at first site | |||
| 2-4 | 28 (27.5) | 19 (22.4) | .70 |
| 5-6 | 28 (27.5) | 26 (30.6) | |
| 7-10 | 46 (45.1) | 40 (47.1) | |
| Baseline worst pain score at second site (n = 15 responders and 17 nonresponders) | |||
| 2-4 | 8 (53.3) | 8 (47.1) | NA |
| 5-6 | 2 (13.3) | 2 (11.8) | |
| 7-10 | 5 (33.3) | 7 (41.2) | |
| First site of painful bone lesion | |||
| Pelvis and hips | 36 (35.3) | 22 (25.9) | NA |
| Spine | |||
| Lumbosacral | 19 (18.6) | 16 (18.8) | |
| Cervical | 1 (1.0) | 2 (2.4) | |
| Thoracic | 17 (17.6) | 12 (14.1) | |
| Limbs | |||
| Upper | 2 (2.0) | 4 (4.7) | |
| Lower | 4 (3.9) | 7 (8.2) | |
| Other | 23 (22.5) | 22 (25.9) | |
| Second site of painful bone lesion (n = 15 responders and 17 nonresponders) | |||
| Pelvis and hips | 3 (20.0) | 4 (23.5) | NA |
| Spine | |||
| Lumbosacral | 2 (13.3) | 3 (17.6) | |
| Cervical | 0 | 0 | |
| Thoracic | 7 (46.7) | 3 (17.6) | |
| Limbs | |||
| Upper | 0 | 1 (5.9) | |
| Lower | 1 (6.7) | 3 (17.6) | |
| Other | 2 (13.3) | 3 (17.6) | |
Abbreviation: NA, not applicable.
a
Data are presented as number (percentage) of patients unless otherwise indicated.
b
P value for comparison of responders and nonresponders to radiotherapy for patients with day 42 quality-of-life data.