Protein spectra from RayBio L-Series Human 507 (507 proteins) and 493 (493 proteins) antibody arrays. Representative images from human antibody arrays demonstrating the reactivity of pooled serum samples to arrays L series (1,000 proteins) in healthy controls and RSA patients. Each protein was measured in duplicate. A total of eight of significantly different factors on the microarrays are marked in elliptical boxes. IGFBP-rp1/IGFBP-7, insulin-like growth factor-binding protein-related protein 1/insulin-like growth factor-binding protein 7; Dkk3, Dickkopf-related protein 3; RAGE, receptor for advanced glycation end products; RSA, recurrent spontaneous abortion; TOPORS, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase; C2, complement C2; RECK, reversion-inducing-cysteine rich protein with kazal motifs.