Table IV.
Identification of 13 mitochondrial proteins downregulated in the high fat and high cholesterol diet group, compared with the control group, using isobaric tags for relative and absolute quantitation labeling technology.
| Accession no. | Protein name | Gene name | Fold change |
|---|---|---|---|
| tr|F1LMQ2|F1LMQ2_RAT | Farnesyl pyrophosphate synthase | FPPS | 0.46 |
| sp|O35760|IDI1_RAT | Isopentenyl-diphosphate δ-isomerase 1 | Idi1 | 0.47 |
| tr|Q5PQZ9|Q5PQZ9_RAT | NADH dehydrogenase [ubiquinone] 1 subunit C2 | Ndufc2 | 0.64 |
| sp|P11951|CX6C2_RAT | Cytochrome c oxidase subunit 6C-2 | Cox6c2 | 0.64 |
| tr|B2RYX1|B2RYX1_RAT | Cytochrome b-c1 complex subunit 9 | Uqcr10 | 0.65 |
| tr|D3ZCZ9|D3ZCZ9_RAT | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6 | Ndufs6 | 0.65 |
| sp|Q63362|NDUA5_RAT | NADH dehydrogenase [ubiquinone] 1α subcomplex subunit 5 | Ndufa5 | 0.66 |
| tr|D4A4P3|D4A4P3_RAT | NADH dehydrogenase [ubiquinone] 1β subcomplex subunit 3 | Ndufb3 | 0.69 |
| tr|B0M1Q8|B0M1Q8_RAT | Cytochrome b | CytB | 0.72 |
| tr|D3ZS58|D3ZS58_RAT | NADH dehydrogenase [ubiquinone] 1α subcomplex subunit 2 | Ndufa2 | 0.72 |
| tr|D4A565|D4A565_RAT | NADH dehydrogenase (ubiquinone) 1β subcomplex, 5 | Ndufb5 | 0.72 |
| tr|Q06QA1|Q06QA1_RAT | NADH-ubiquinone oxidoreductase chain 5 | ND5 | 0.76 |
| sp|Q6PCT8|DHSD_RAT | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit | Sdhd | 0.80 |
Fold changes of ≤0.8 and P<0.05 for all statistical data.