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TEM snapshots of CtsL degradation of α-syn fibrils. α-Syn fibrils (15 μM) formed at pH 5 before (A and B) and after (C-G) Cts L proteolysis ([CtsL] = 150 nM at 37 °C for 4 h). Jagged fibril ends (arrows), fibril hole (circle) and missing fibril density (line bar) are shown.
