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. 2017 Jun 27;16(3):2522–2528. doi: 10.3892/mmr.2017.6862

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Altered expression of miR-21, PDCD4 and PTEN following SCI. (A) miR-21 expression levels were significantly reduced 4 and 8 h, and 1 day post-SCI compared with the control group, whereas miR-21 expression levels were significantly increased at days 3 and 7 post-SCI compared with the control group. (B) Representative western blot images and quantification of (C) PDCD4 and (D) PTEN protein expression levels. The expression levels of PDCD4 and PTEN were decreased significantly at days 3 and 7 post-SCI compared with the control group. Data are expressed as the mean ± standard deviation (n=4/group). *P<0.05 vs. control group. miR-21, microRNA-21; SCI, spinal cord injury; PDCD4, programmed cell death 4; PTEN, phosphatase and tensin homolog; con, control.