Proportions of human immunodeficiency virus (HIV)-positive (HIV+) and HIV-negative (HIV–) individuals (a) below/above the recommended systolic blood pressure (SBP) and (b) cholesterol thresholds, and proportions using antihypertensive and lipid-lowering medication; (a) illustrates the proportion of individuals below (green) or above (red) the recommended SBP threshold for treatmentb among HIV-positive and HIV-negative participants, with the bars in grey indicating the proportion of individuals who do (upward diagonal lines) or do not (solid fill) use antihypertensive medication, stratified by cardiovascular risk group; (b) shows the proportion of individuals below (green) or above (red) the recommended cholesterol thresholds for treatmentc among HIV-positive and HIV-negative participants, with the bars in grey demonstrating the proportion of individuals who do (upward diagonal lines) or do Figure 2. Continued not (solid fill) use lipid-lowering medication, stratified by cardiovascular risk group. The numbers below the graph show the number of participants within each group. Data are presented as percentages. High risk: 10-year cardiovascular risk≥20% or 10-year cardiovascular risk 10–20% with additional cardiovascular risk factors; low risk: 10-year cardiovascular risk<10%; moderate risk: 10-year cardiovascular risk 10–20% without additional cardiovascular risk factors. LDL-c: low-density lipoprotein cholesterol; TC/HDL-ratio, total cholesterol/ high-density lipoprotein cholesterol ratio.
aFisher’s exact test; group comparison of HIV-positive versus HIV-negative individuals below or above the recommended threshold for treatment in each risk stratum.
bSBP thresholds differ between and within the different subgroups: (a) SBP > 180 mm Hg in participants with primary prevention low 10-year cardiovascular risk or moderate 10-year cardiovascular risk participants with no additional risk factors; or (b) SBP > 160 mm Hg in participants aged ≥80 years with primary prevention high 10-year cardiovascular risk; or (c) SBP > 140 mm Hg in participants aged <80 years with primary prevention high 10-year cardiovascular risk, or those eligible for secondary prevention;
cPlasma lipid levels are above the threshold when (a) TC/HDL-ratio>8 (regardless of cardiovascular risk), or (b) LDL-cholesterol>2.5 mmol/l in participants with primary prevention high 10-year cardiovascular risk, or eligible for secondary prevention.