Fig 1.

Patient 8. 3T axial (A) and sagittal (B–E) 3D FSPGR, 7T 3D SWAN (F), and magnified images (G, G+1, H), 7T axial 2D TBE FSE-IR (I) and magnified images (L and M). A, Mild cortical thickening in the right frontal operculum. Contiguous sagittal sections across the frontal operculum and the Sylvian fissure on the right (B and D) and left (C and E) sides provide a better comparative view of the morphologic characteristics of malformed-versus-normal cortex. B, An abnormal right Sylvian fissure (arrow), which is vertically oriented, shortened, and bordered by thick and irregular cortex. D, Thickening of the cortex in the inferior frontal gyrus and superior temporal gyrus (arrows). F, Two contiguous expanded views, from caudal (G) to rostral (G+1), provide ultra-high-resolution details of the right frontal operculum, which are not visible at 3T (A–E), substantiating the presence of a polymicrogyric cortex. H, A magnification of the homologous contralateral region clearly enhances the appreciation of the difference in folding of the polymicrogyric and normal cortex. I, Magnifications (L and M) show a hypointense line representing the gray-white matter interface and provide a high definition of the polymicrogyric (L, arrows) and normal (M) cortex, making it easier to appreciate irregularities in thickness and folding of the polymicrogyric cortex.