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. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Proteomics. 2016 Mar;16(5):700–714. doi: 10.1002/pmic.201500355

Table 1.

A list of common modifications with isobaric delta masses

Number Modification Delta mass (Da) Composition Alternative explanation
1 Amidation   −0.984016 HN O(−1) D to N, E to Q
2 Deamidation     0.984016 H(−1) N(−1) O N to D, Q to E
3 Methylation   14.01565 H(2) C G to A, D to E, V to I/L, S to T, N to Q
4 Formylation   27.994915 C O D to S, E to T
5 di-Methylation   28.0313 H(4) C(2) Ethyl, A to V, C to M
6 S-nitrosylation   28.990164 H(−1)NO V to Q
7 Sulfide   31.972071 S V to M, A to C
8 Di-Oxidation   31.989829 O(2) P to E
9 Acetylation   42.010565 H(2) C(2) O S to E
10 Tri-Methylation   42.04695 H(6) C(3) Propyl, A to L/I, G to V
11 Carbamylation   43.005814 HCNO A to N
12 Carboxylation   43.989829 C O(2) A to D
13 Propionylation   56.026215 H(4) C(3) O Acrolein adduct
14 Carbamidomethylation   57.021464 H(3) C(2) N O A to Q, G to N, addition of glycine
15 Carboxymethylation   58.005479 H(2) C(2) O(2) A to E, G to D
16 Methylmalonylation 100.016044 H(4) C(4) O(3) Succinylation
17 Ubiquitin remnant (di-Gly) 114.042927 H(6) C(4) N(2) O(2) Double carbamidomethylation, addition of asparagine