Table 1.

Binding affinities (K_D = 1/K_a) of hOGG1 for nonspecific DNA and specific DNA sequences at various concentrations of potassium acetate^a

[K+] (mM)	1/Ka (µM)
	DN	DSb
30	0.11 ± 0.01	0.060 ± 0.01
	0.18 ± 0.06b
50	0.12 ± 0.04	0.08 ± 0.01
	0.11 ± 0.03b
75	0.16 ± 0.02	0.15 ± 0.02
	0.26 ± 0.04b
100	0.15 ± 0.02	0.9 ± 0.4
	0.7 ± 0.02b
150	0.39 ± 0.03	1.3 ± 0.1
	1.1 ± 0.2b
200	0.64 ± 0.05	2.6 ± 0.2
	1.4 ± 0.3b
300	0.9 ± 0.1	--c

^aErrors were estimated from three independent experiments for 50 mM K⁺, 150 mM K⁺, and 300 mM K⁺. The other errors are obtained from the standard deviation of the data from the best non-linear fit.

^bThese values were determined using K249Q hOGG1.

^cNot determined.