Table 2.
Slope (N)b | Kanon (M−1)c | |
---|---|---|
KaN | −1.0 ± 0.2 | 4.0 ± 0.1 × 105 |
−1.3 ± 0.3d | 8.8 ± 0.6 × 104d | |
KaTATA | −1.9 ± 0.4 | 2.6 ± 0.2 × 104 |
KaGC | −2.0 ± 0.5 | 2.5 ± 0.3 × 104 |
KaGCGC | −1.8 ± 0.4 | 5.4 ± 0.4 ×104 |
KaS | −2.1 ± 0.3d | 1.5 ± 0.1 × 104d |
All experiments were conducted using WT hOGG1 unless otherwise noted and the error is derived from the linear fit.
The slope (N) obtained from nonlinear regression fitting to eq 3.
Kanon is the extrapolated value of the Ka to the condition of 1 M [K+].
These values were determined using K249Q hOGG1.