Exemplary Ahringer library targets for detecting changes in RNAi sensitivity
| Target | Phenotype | Strength of RNAi** |
|---|---|---|
| dpy-13 | Dumpy | weak |
| unc-73 | Curled dumpy | weak |
| lir-1 | Lethal or larval arrest | medium |
| dpy-11 | Dumpy | strong |
| pos-1 | Embryonic lethal | strong |
| unc-22 | Twitching | strong |
**
A “weak” RNAi target indicates that the bacterial colony containing that vector from the Ahringer library only induces a RNAi knockdown in an enhanced RNAi strain, whereas a “strong” RNAi target means that only a RNAi-attenuated or -defective strain would not exhibit RNAi knockdown.