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. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Nat Chem. 2013 Nov 3;5(12):1049–1057. doi: 10.1038/nchem.1788

Figure 1. Natural products and pharmaceutical agents bearing complex cyclopentanes and accessible cyclopentyl systems employing the described NCMAL process.

Figure 1

a, Bioactive natural products and drugs including polycyclics possessing highly substituted cyclopentane cores (red). b, Natural products possessing β-lactone-fused cyclopentanes (red). c, Several diverse cyclopentane scaffolds accessible by the described nucleophile-catalyzed, Michael-aldol-β-lactonization (NCMAL) process.