Table 1.

Recommended evaluation prior to initiation of growth hormone therapy (hGH) in adults with Prader-Willi syndrome (PWS) [46].

Anthropometrics	Weight
	Height
	BMI
	Waist circumference
	Skin fold thickness if possible
Endocrine Evaluation	Baseline IGF-1
	Consider provocative GH testing
	Thyroid function assessment
	Consider screening for adrenal insufficiency
Metabolic Evaluation	Hemoglobin A1c
	Fasting glucose
	Fasting insulin
	Consider OGTT if other risk factors are present
Obesity Related Evaluation	Fasting lipids
	AST, ALT
	Blood Pressure
Sleep Oximetry	Polysomnography preferred
Baseline Evaluations to Help Assess Benefit of Therapy	Body composition (DXA or biochemical impedance)
	Cognitive status
	Motor function ( physiotherapy/occupational therapy referral)